(credit: Art Writ)
Let’s get something straight from the start: vaccines are good. Let’s be completely clear about that. But sometimes some people have adverse reactions to them—no, not autism, but things like diarrhea, nausea, fatigue, maybe a sore arm. And when the vaccinated (or their parents) complain to their friends about it, their friends might be tempted to skip their own vaccinations.
It would be nice to know in advance who might respond negatively to a vaccine so they could be warned and treated. A recent paper out of London harnesses advances in high-throughput analytical technologies, informatics, and biostatistics to begin to do just that.
Researchers treated 178 healthy adult volunteers with a vaccine against the H1N1 “swine flu” that circulated in 2009. They took blood and urine from the volunteers one week before their shots, the day of their shots, and then one day, one week, two weeks, and again 63 days afterward.
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Antibodies to our own proteins may predict adverse vaccine responses