Researchers have discovered how an abundant class of RNA genes, called lncRNAs can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome — a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the mechanism of action for lncRNA genes. - Source
How an RNA gene silences a whole chromosome